Potential Anti-Aging Effects of a Dietary Supplement From the Algal-Derived Omega-3 DHA in Aged SAMP 8 Mice.

Ming-Yu Chou, I-Hung Lin, Chia-Jung Chen, Ting-Jian Guo, Che-An Lin, Dao-Na Yang, Po-Hsien Li, Yu-Chen Li, Mei-Due Yang, Chieh-Chang Tien, Ruei-Ze Lin, Ching-Hsin Chi, Shih-Yi Wang, Ming-Fu Wang

Wenzhou Medical University Big One Health Development Research Institute Wenzhou City Zhejiang Province China.Wenzhou Medical University Big One Health Development Research Institute Wenzhou City Zhejiang Province China. · pubmed

Paper

Abstract

This study investigated the anti-aging effects of algal Omega3-DHA in senescence-accelerated mice (SAM). Male and female SAMP8 mice (3 months old) were divided into a control group and four experimental groups (1× or 2× algal Omega3-DHA, with/without phospholipids). The mice were orally administered test samples dissolved in corn oil daily for 13 weeks. Aging scores were significantly lower in male mice across all experimental groups and in female mice in the phosphatidylcholine (PC) and phosphatidylserine (PS) (

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Research summary

The paper claims that dietary supplementation with algal Omega-3 DHA can reduce aging scores in SAMP8 mice. This study is relevant as it explores a potential intervention that may address mechanisms of aging rather than merely treating age-related symptoms.

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