Update of the Novara Cohort Study (NCS): protocol evolution of a population-based longitudinal study on ageing in Northern Italy - cohort profile.

Silvia Vittoria Cracas, Giulia Garro, Jacopo Venetucci, Marco Martorana, Annamaria Antona, Valentina Bettio, Davide Rossato, Luca Briacca, Erica Viola, Silvia Caristia, Vittoria Colombo, Lucrezia Capuzzi, Chiara Roveda, Marco Varalda, Roberta Rolla, Sara Sacchetti, Paolo Amedeo Tillio, Daniela Capello, Fabrizio Faggiano

Department for Sustainable Development and Ecological Transition, University of Eastern Piedmont, Vercelli, Italy [email protected] for Sustainable Development and Ecological Transition, University of Eastern Piedmont, Vercelli, Italy [email protected]. · pubmed

Paper

Abstract

The Novara Cohort Study (NCS) was established to investigate the biological, psychological and social factors that influence ageing in the general population. The study aims to identify early risk factors for frailty, allostatic load and cognitive decline, and to uncover molecular and functional markers of accelerated biological ageing. NCS addresses the need for detailed life-course data from Southern Europe to support personalised prevention and early diagnosis, and to promote healthy longevity.

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Research summary

The Novara Cohort Study aims to identify early risk factors for frailty and cognitive decline related to ageing. The study addresses the biological, psychological, and social factors influencing ageing, which is crucial for understanding and potentially mitigating the root causes of aging.

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