Novel proteomic subtypes of frailty with distinct molecular patterns and prognosis.

Zhenyi Xu, Ce Wang, Jiaofeng Wang, Jie Chen, Xiaojun Wang, Zhijun Bao, Yan Zhang

Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital, Fudan University, Shanghai, 200040, China; Shanghai Institute of Geriatric Medicine, Huadong Hospital, Fudan University, Shanghai, 200040, China. · pubmed

Paper

Abstract

The frailty phenotype has limitations in capturing the biological heterogeneity of the condition. Our study identified subtypes of frailty based on proteomics and examined their associations with several adverse outcomes.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study identifies novel proteomic subtypes of frailty that correlate with adverse outcomes. This research is relevant as it seeks to understand the biological underpinnings of frailty, which is a significant aspect of aging and can inform interventions aimed at improving healthspan.

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