Herpes zoster vaccination and incident dementia in Canada: an analysis of natural experiments.

Michael Pomirchy, Seunghun Chung, Christian Bommer, Stephenson Strobel, Pascal Geldsetzer

Division of Primary Care and Population Health, Department of Medicine, Stanford University, Stanford, CA, USA.Division of Primary Care and Population Health, Department of Medicine, Stanford University, Stanford, CA, USA. · pubmed

Paper

Abstract

Two natural experiment studies have found evidence that live attenuated herpes zoster vaccination prevents or delays dementia onset. We aimed to determine the effect of live attenuated herpes zoster vaccination on incident dementia diagnoses among people aged 70 years and older using a natural experiment in Ontario, Canada, and to triangulate these findings, using a second natural experiment in Ontario and a quasi-experimental approach that uses data from multiple Canadian provinces.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that live attenuated herpes zoster vaccination may prevent or delay the onset of dementia in older adults. This research is relevant as it explores a potential intervention that could impact age-related diseases, specifically dementia, which is a significant concern in the context of aging and longevity.

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