Integrated multi-omics identifies MCRS1 as a causal hub linking aging, metabolic syndrome, and breast cancer progression.

Yiying Tao, Xibing Ding, Wei Xuan, Hao Zhu, Xiaohua Liu, Yuqing Chen, Jialin Wu, Jing Du, Jie Tian, Guojun Qian

Key Laboratory of Anesthesiology (Shanghai Jiao Tong University, Ministry of Education), Department of Anesthesiology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. · pubmed

Paper

Abstract

Aging and metabolic syndrome (MetS) are intertwined risk factors for breast cancer (BC), but the core molecular nexus integrating these states is unknown. This study aimed to identify and validate a causal driver at this intersection.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that MCRS1 is a causal hub linking aging, metabolic syndrome, and breast cancer progression. This research addresses the molecular connections between aging and disease, which is pertinent to understanding the root causes of aging and its related pathologies.

Author of this paper? Send a correction.