The role of AGEs in skeletal muscle atrophy and the beneficial effects of exercise.

Xinru Wu, Shuai Hu, Wei Miao, Fei Shen, Li Jiang

Department of Internal Medicine, Kunshan Integrated TCM and Western Medicine Hospital, Suzhou, China.Department of Internal Medicine, Kunshan Integrated TCM and Western Medicine Hospital, Suzhou, China. · pubmed

Paper

Abstract

Advanced Glycation End Products (AGEs) are associated with the aging and atrophy of skeletal muscle. Their pathogenic mechanism mainly involves the binding of AGEs to their own receptors, which in turn triggers a series of pathological reactions. Exercise is considered an effective intervention method, as it can regulate the level of AGEs, thereby alleviating skeletal muscle atrophy.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that exercise can regulate the level of Advanced Glycation End Products (AGEs) to alleviate skeletal muscle atrophy. This research is relevant as it addresses the mechanisms of aging and muscle degeneration, which are critical factors in longevity and age-related decline.

Author of this paper? Send a correction.