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RESEARCH PAPER / 2026-01-10

Mitochondrial Health Through Nicotinamide Riboside and Berberine: Shared Pathways and Therapeutic Potential.

Federico Visalli, Matteo Capobianco, Francesco Cappellani, Lorenzo Rapisarda, Alfonso Spinello, Alessandro Avitabile, Ludovica Cannizzaro, Caterina Gagliano, Marco Zeppieri

Department of Ophthalmology, University of Catania, 95123 Catania, Italy.Department of Ophthalmology, University of Catania, 95123 Catania, Italy. · pubmed

Abstract

Mitochondrial dysfunction represents a central hallmark of aging and a broad spectrum of chronic diseases, ranging from metabolic to neurodegenerative and ocular disorders. Nicotinamide riboside (NR), a vitamin B

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that nicotinamide riboside and berberine can improve mitochondrial health through shared pathways. This research addresses mitochondrial dysfunction, a key factor in the aging process and age-related diseases, suggesting potential therapeutic strategies for longevity.

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