Calorie Restriction Suppresses Premature Ageing in Pro-Apoptotic Yeast Mutants Through an Autophagy-Independent Mechanism.

Benedetta Caraba, Mariarita Stirpe, Vanessa Palermo, Alessia Ayala Alban, Arianna Montanari, Michele Maria Bianchi, Claudio Falcone, Cristina Mazzoni

Department of Biology and Biotechnologies "C. Darwin", Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Roma, Italy. · pubmed

Paper

Abstract

The budding yeast

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Research summary

Calorie restriction in pro-apoptotic yeast mutants leads to suppression of premature aging through an autophagy-independent mechanism. This research explores a potential mechanism of aging and lifespan extension, which is directly relevant to the field of longevity.

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