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RESEARCH PAPER / 2026-01-08

Interaction between physical activity and deficit-based frailty on all-cause mortality in older adults: a prospective study of five population-based cohorts.

Zheng Zhu, Xu Zhou, Mingling Chen, Chun Dou, Dong Liu, Lijie Kong, Chaojie Ye, Min Xu, Yu Xu, Mian Li, Zhiyun Zhao, Jie Zheng, Jieli Lu, Yuhong Chen, Weiqing Wang, Guang Ning, Yufang Bi, Tiange Wang

Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. · pubmed

Abstract

Whether leisure-time physical activity modifies the association between frailty and mortality in older adults is unclear.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that leisure-time physical activity may influence the relationship between frailty and mortality in older adults. This research is relevant as it explores the interaction between physical activity and frailty, which are both critical factors in understanding aging and longevity.

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