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RESEARCH PAPER / 2026-01-07

Ultraviolet radiation reshapes the transcriptomic landscape of human skin aging: Insights from a multi-age comparative study.

Jiaqi Zhang, Xueli Jia, Qitian Fu, Xiaofeng Bai, Jun Wang, Yi Qin, Jie Yang, Fengwei Qi, Yao Pan

Department of Cosmetics, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 102488, China.Department of Cosmetics, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 102488, China. · pubmed

Abstract

Skin aging arises from both intrinsic processes and extrinsic factors, with ultraviolet (UV) radiation being the primary extrinsic cause of photoaging. However, the molecular mechanisms that differentiate these processes across the human lifespan remain incompletely characterized.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the molecular mechanisms of skin aging influenced by UV radiation across different ages. This research is relevant as it addresses the extrinsic factors contributing to aging, which could inform strategies for longevity and age-related interventions.

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