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RESEARCH PAPER / 2026-01-05

Longevity, Centenarians, and Lifestyle: Any ''Tips'' to Live Longer?

Claudia Vetrani, Evelyn Frias-Toral, Giuseppe Annunziata, Feliciana Amatrudo, Davide Mayol, Rosario Suárez, Ludovica Verde, Mariarosaria Negri, Prisco Piscitelli, Annamaria Colao, Giovanna Muscogiuri, Luigi Barrea

Department of Psychology and Health Science, Pegaso Telematic University, Naples, Italy. · pubmed

Abstract

In this narrative review, we provide an overview of the current understanding of the lifestyle factors that are associated with longevity and healthy aging, having Centenarians as a reference population.  RECENT FINDINGS: Despite cultural differences, Centenarians exhibit common behavioural patterns and lifestyle habits believed to promote longevity. In particular, plant-based dietary patterns provide antioxidant and anti-inflammatory properties, thus counteracting physiological and pathophysiological processes relating to unsuccessful aging. Regular physical activity reduces inflammation and preserves lean mass, leading to metabolic fitness and adequate body composition. Finally, meditation practices have been shown to reduce stress reactivity and inflammatory responses related to cortisol secretion. This multifactorial approach might improve the health status and life quality of older people as a priority of the continuous increase of the ageing population.  For the promotion of successful aging, lifestyle interventions should follow a multifactorial approach. This review offers specific recommendations to promote longevity in the general population, including plant-based eating patterns, physical activity and psychological well-being.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper suggests that a multifactorial approach involving plant-based diets, physical activity, and psychological well-being can promote longevity. This review is relevant as it addresses lifestyle factors that may contribute to successful aging and longevity, focusing on preventative measures rather than merely treating age-related diseases.

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