Age-independent and targetable transcription factor networks regulating CD8

Paolo S Turano, Elizabeth Akbulut, Hannah K Dewald, Themistoklis Vasilopoulos, Patricia Fitzgerald-Bocarsly, Utz Herbig, Ricardo Iván Martínez-Zamudio

Rutgers-New Jersey Medical School, Center for Cell Signaling, Department of Microbiology, Biochemistry and Molecular Genetics, 205 South Orange Avenue, Newark, NJ, USA. · pubmed

Paper

Abstract

The age-related decline in immunity is accompanied by the accumulation of senescent CD8

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that age-independent transcription factor networks can regulate CD8 T cell function. This research addresses mechanisms underlying the age-related decline in immunity, which is a critical aspect of aging and longevity.

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