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RESEARCH PAPER / 2026-01-02

Bioconverted Red Ginseng Protects Liver Functions and Alters Insulin Homeostasis-Associated Gut Microbiome Composition in Aged Mice.

Da-Yeon Lee, Jing Liu, Su-Jeong Lee, Gopal Lamichhane, Ashton Swayze, Guolong Zhang, Tae Young Kim, Josephine M Egan, Yoo Kim

Department of Nutritional Sciences, Oklahoma State University, Stillwater, OK, United States. · pubmed

Abstract

Aging is associated with progressive functional deteriorations that affect the metabolic dysfunction in the liver and the alteration of the gut microbial environment. Red ginseng (RG) is one of the widely investigated ginseng products known for its antiaging properties, derived from its unique bioactive compounds known as ginsenosides.

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Research summary

Bioconverted red ginseng improves liver function and alters gut microbiome composition in aged mice. The study addresses metabolic dysfunction and gut microbiome changes associated with aging, which are relevant to understanding and potentially mitigating age-related decline.

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