Diet quality and nutritional adequacy during a 2-year calorie restriction intervention: the Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy 2 trial.

Susan B Racette, Rachel E Silver, Valene Garr Barry, Jasmyn J DeGraff, Jordan A Gunning, Maryam Kebbe, Cheryl H Gilhooly, Sai Krupa Das

College of Health Solutions, Arizona State University, Phoenix, AZ, United States; Program in Physical Therapy and Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States. Electronic address: [email protected] of Health Solutions, Arizona State University, Phoenix, AZ, United States; Program in Physical Therapy and Department of Medicine, Washington University School of Medicine, St. Louis, MO, United States. Electronic address: [email protected]. · pubmed

Paper

Abstract

Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy (CALERIE) was the first randomized controlled trial of calorie restriction (CR) on biomarkers of aging and cardiometabolic health in humans without obesity.

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Research summary

The paper claims that a 2-year calorie restriction intervention improves diet quality and nutritional adequacy, potentially influencing biomarkers of aging and cardiometabolic health. This research is relevant as it investigates calorie restriction, a key intervention in longevity studies, and its effects on aging-related health markers.

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