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RESEARCH PAPER / 2025-12-31

Sex-Specific Association of Telomere Length with Individualized Expected Years of Life Lost among 203,731 Males and 241,668 Females.

Fei Fei Xu, Chen Jie Li, Yi Fan Wang, Xiao Wang, Yumnah Babar, Shuang Liang, Fan Yang, Zha Zheng He, Hong Gang Yi, Jun Cheng Dai

Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, China.Department of Epidemiology, Center for Global Health, School of Public Health, Nanjing Medical University, Nanjing 211166, Jiangsu, China. · pubmed

Abstract

Telomere length is a key aging biomarker, but its sex-specific impact on individualized life expectancy remains uncertain. This study explores sex differences in leukocyte telomere length (LTL) and individualized expected years of life lost (YLL).

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that there are sex-specific associations between leukocyte telomere length and individualized expected years of life lost. This research is relevant as it investigates telomere length, a biomarker of aging, and its implications for life expectancy, contributing to the understanding of aging mechanisms.

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