Association between methylmalonic acid and Alpha-Klotho in American adults: A cross-sectional study.

Ronghui Bao, Hongyan Qi, Lei Liao, Qinqin Yu, Jie Li, Rong Liu, Chang Zhou

The First College of Clinical Medical Science, China Three Gorges University, Yichang, China.The First College of Clinical Medical Science, China Three Gorges University, Yichang, China. · pubmed

Paper

Abstract

Methylmalonic acid is a surrogate biomarker of mitochondrial dysfunction and oxidative stress. Serum soluble α-Klotho, as a key anti-aging factor, is regarded as one of the biomarkers of aging. The correlation between Methylmalonic Acid (MMA) and Alpha-Klotho (α-Klotho) remains uncertain. This study aims to explore the relationship between MMA and Alpha-Klothoα-Klotho in American adults.

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Research summary

This study investigates the relationship between methylmalonic acid and alpha-Klotho in American adults. The focus on biomarkers associated with mitochondrial dysfunction and aging factors aligns with the exploration of mechanisms underlying aging and longevity.

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