Association between 24-h time-use composition and brain age: The IGNITE study.

Audrey M Collins, Maddison L Mellow, Lu Wan, Ashleigh E Smith, Lauren E Oberlin, Kelsey R Sewell, Neha P Gothe, Jason Fanning, Jairo H Migueles, Dorothea Dumuid, Aaron Miatke, John M Jakicic, Chaeryon Kang, George Grove, Haiqing Huang, Bradley P Sutton, Anna L Marsland, M Ilyas Kamboh, Arthur F Kramer, Charles H Hillman, Eric D Vidoni, Jeffrey M Burns, Edward McAuley, Kirk I Erickson

AdventHealth Research Institute Department of Neuroscience AdventHealth Orlando Florida USA.AdventHealth Research Institute Department of Neuroscience AdventHealth Orlando Florida USA. · pubmed

Paper

Abstract

The relationships between 24-h time-use composition (i.e., sleep, sedentary behavior, light physical activity, and moderate-to-vigorous physical activity [MVPA]) and brain morphology in older adulthood remain poorly understood. We examined associations between 24-h time-use composition and brain age using compositional data analysis, predicting that 24-h time use would be associated with brain age and that a greater amount of time engaged in MVPA would drive associations with younger brain age.

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Research summary

Greater engagement in moderate-to-vigorous physical activity is associated with a younger brain age. This paper is relevant as it explores the relationship between physical activity and brain health, which can contribute to understanding mechanisms that influence aging and longevity.

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