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RESEARCH PAPER / 2025-12-25

Probiotics intervention reduces oxidative stress-driven myocardial injury.

Olia Hamzeh, Sahar Rostami-Mansoor, Farideh Feizi, Nasrin Nosratiyan, Mehrdad Halaji

Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. of Iran.Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, I.R. of Iran. · pubmed

Abstract

Aging is a significant risk factor for cardiovascular diseases, characterized by progressive structural and functional decline in the heart. In addition to oxidative stress, which is a key player in aging, recent research suggests that the gut-heart axis may contribute to age-related cardiac dysfunction, with probiotics emerging as a potential therapeutic strategy. While probiotics have been extensively studied for their benefits in metabolic, neurological, and immune disorders, their impact on cardiac aging remains largely unexplored. This study investigates the cardioprotective effects of

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Research summary

Probiotics intervention can reduce oxidative stress-driven myocardial injury in aging hearts. This study addresses the gut-heart axis and its potential role in age-related cardiac dysfunction, which aligns with the exploration of therapeutic strategies targeting the root causes of aging.

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