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RESEARCH PAPER / 2025-12-24

Translating Geroscience Into Clinical Longevity Dermatology: From Mechanisms of Aging to Skin-Centered Interventions.

Diala Haykal

Centre Médical Laser Palaiseau, Private Practice, Palaiseau, France.Centre Médical Laser Palaiseau, Private Practice, Palaiseau, France. · pubmed

Abstract

Longevity medicine is an emerging clinical framework aimed at extending healthspan by targeting the biological mechanisms of aging rather than treating disease in isolation. Geroscience, which investigates the molecular and cellular pathways linking aging to chronic pathology, provides the scientific foundation for this approach. Dermatology is uniquely positioned within this paradigm, as the skin represents both a visible marker of biological aging and an accessible source of biomarkers.

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Research summary

The paper claims that dermatology can leverage geroscience to develop skin-centered interventions targeting the biological mechanisms of aging. This research is relevant as it explores the intersection of aging mechanisms and dermatological practices, aiming to address the root causes of aging rather than merely treating symptoms.

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