Therapeutic effects of Total flavonoids of Epimedium Folium on sarcopenia via modulation of gut microbiota and bile acid metabolism.

Yujie Zhang, Zhe Pan, Jiewen Shi, Jingjing Zhang, Yongli Chai, Ye Zhao, Wei Liu, Wei''an Yuan

Clinical Research Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road Pudong New District, Shanghai, 201203, China. · pubmed

Paper

Abstract

The total flavonoids of Epimedii Folium (Epimedium brevicornu Maxim.) are the main active component, and have unique advantages in sarcopenia intervention. Nevertheless, its efficacy and mechanism of action have not been reported in the literature.

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Research summary

The paper claims that total flavonoids of Epimedium Folium can improve sarcopenia through modulation of gut microbiota and bile acid metabolism. This research addresses sarcopenia, which is a significant age-related condition, and explores potential mechanisms that could contribute to healthier aging.

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