Oral short-chain fatty acid-producing bacteria may be associated with biological age and cognition among the oldest old.

Tim Wehnes, Weilan Wang, Jian Hua Tay, Lihuan Guan, Lei Feng, Chun Man Roger Ho, Tze Pin Ng, Brian K Kennedy, Ashok Venkitaraman, Woon-Puay Koh, Yap Seng Chong, Andrea B Maier

Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. · pubmed

Paper

Abstract

Biological age derived from DNA methylation (mAge) reflects aging-related physiological changes and the risk of age-related diseases. However, the association between oral microbiome and mAge remains unclear.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that oral short-chain fatty acid-producing bacteria are associated with biological age and cognition among the oldest old. This research is relevant as it explores the relationship between the oral microbiome and biological aging, potentially addressing root causes of aging and age-related diseases.

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