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RESEARCH PAPER / 2025-12-18

Association between biological aging and stroke and all-cause mortality: A population-based cross-sectional study and Mendelian randomization analysis.

Zijie Wang, Xinwei Zhao, Yan Ma

The Second Affiliated Hospital Of Tianjin University Of TCM, Tianjin, 300143, China.The Second Affiliated Hospital Of Tianjin University Of TCM, Tianjin, 300143, China. · pubmed

Abstract

Stroke is a major acute cerebrovascular disorder and a leading cause of disability and death, for which ageing is a key risk factor. However, individuals of the same chronological age differ markedly in cerebrovascular vulnerability. This study aimed to investigate the association between biological aging and stroke risk and prognosis using several validated aging metrics.

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Research summary

The paper investigates the association between biological aging and stroke risk and prognosis using validated aging metrics. This research is relevant as it explores biological aging as a risk factor for stroke, which is a significant age-related disease, and contributes to understanding the underlying mechanisms of aging.

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