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RESEARCH PAPER / 2025-12-13

Associations of life course social determinants of health, social mobility with cognitive function and roles of social participation and lifestyle: a multicohort study.

Xiang Li, Zhongxuan Wang, Qi Wang, Chunying Fu, Bo Xie, Luyi Zhang, Xiaoyu Zhang, Dongshan Zhu

Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China. · pubmed

Abstract

Social determinants of health (SDOH) throughout life are key factors affecting cognitive aging. The long-term effects of life course SDOH and social mobility on cognitive function are not well understood. We aimed to examine how stage-specific and cumulative SDOH and social mobility related to cognitive function and decline, considering the roles of lifestyle and social participation.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that life course social determinants of health and social mobility are associated with cognitive function and decline, influenced by lifestyle and social participation. This research is relevant as it explores the long-term effects of social factors on cognitive aging, which is a critical aspect of understanding and potentially mitigating age-related decline.

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