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RESEARCH PAPER / 2025-12-10

Osteosarcopenia, bone-muscle interactions, and frailty risk: A prospective cohort study of community-dwelling older adults.

Mizhgan Fatima, Ben Kirk, Sara Vogrin, Jason Talevski, Sharon Brennan-Olsen, Gustavo Duque

Department of Medicine, Melbourne Medical School, Western Health, University of Melbourne, St Albans, Melbourne, VIC, Australia.Department of Medicine, Melbourne Medical School, Western Health, University of Melbourne, St Albans, Melbourne, VIC, Australia. · pubmed

Abstract

Osteosarcopenia, defined as the co-existence of osteopenia/osteoporosis and sarcopenia, may influence frailty risk in older adults. However, the longitudinal association between osteosarcopenia or its components and frailty remain unclear. This study aimed to address this.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study investigates the relationship between osteosarcopenia and frailty risk in older adults. This research is relevant as it addresses the interplay between age-related conditions that may contribute to frailty, a significant factor in longevity and healthy aging.

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