Epigenetic Aging Clocks and Incident Cardiovascular Outcomes: Results From the MESA.

Shantanu Srivatsa, Noah Rice, James R Pike, Jennifer A Smith, Jingzhong Ding, Yongmei Liu, Matthew Budoff, Ganga S Bey

UNC Chapel Hill School of Medicine Gillings School of Public Health Chapel Hill NC. · pubmed

Abstract

DNA methylation-based aging clocks capture biological aging processes and may improve cardiovascular risk prognostication. However, evidence about epigenetic aging clocks, incident outcomes, and interactions with clinical biomarkers such as coronary artery calcium (CAC) in diverse cohorts are limited.

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Research summary

Epigenetic aging clocks can enhance cardiovascular risk prognostication by integrating with clinical biomarkers. The study addresses biological aging processes, which are central to understanding longevity and age-related diseases.

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