Proteomics mediates the effects of biological aging on the progression of cardio-renal-metabolic comorbidity: a UK biobank cohort study.

Zhijie Lin, Changxi Wang, Zhennan Lin, Kaiyang Lin, Yansong Guo

Department of Cardiology, Shengli Clinical Medical College of Fujian Medical University, , Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, China. · pubmed

Paper

Abstract

Cardio-renal-metabolic (CRM) comorbidity, including cardiovascular disease, chronic kidney disease, and type 2 diabetes mellitus, is prevalent in the population and closely associated with biological aging. However, longitudinal evidence and potential proteomics mediator remain limited.

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Research summary

The paper investigates the role of proteomics in understanding the relationship between biological aging and the progression of cardio-renal-metabolic comorbidity. This study is relevant as it explores biological mechanisms associated with aging and their impact on multiple age-related diseases, contributing to the understanding of aging processes.

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