Genetic and environmental risk factors for major depression in UK women and their association with telomere length longitudinally.

Tsz Yan Wong, Alexandra C Gillett, Leena Habiballa, Rodrigo R R Duarte, Ajda Pristavec, Pirro Hysi, Claire J Steves, Veryan Codd, Timothy R Powell

Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, United Kingdom.Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, United Kingdom. · pubmed

Paper

Abstract

Major depressive disorder (MDD) is more prevalent in women and associated with shorter telomere length, a marker of biological ageing, and an increased risk of age-related disease. However, the precise influence of depression-related genetic and environmental risk factors on telomere dynamics remains a topic of debate.

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Research summary

The paper investigates the relationship between genetic and environmental risk factors for major depression and their association with telomere length. This research is relevant as it explores biological aging markers in the context of mental health, potentially linking depression to mechanisms of aging and age-related diseases.

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