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RESEARCH PAPER / 2025-12-05

The influence of vascular risk factors and aging on choroid plexus enlargement.

Keita Watanabe, Jusei Kudo, Miho Sasaki, Tomohiro Shintaku, Shinya Kakehata, Sera Kasai, Kana Saito, Tatsuya Mikami, Yoshinori Tamada, Shingo Kakeda

Department of Radiology, Kyoto Prefectural University of Medicine, Kyoto, Japan. [email protected]. · pubmed

Abstract

Using a large elderly population cohort, we investigated the relationship between choroid plexus (CP) volume, a potential indicator of glymphatic system activity, and lifestyle-related vascular risk and protective factors, as well as age-related changes in CP volume.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that vascular risk factors and aging influence choroid plexus volume, which may indicate changes in glymphatic system activity. This research is relevant as it explores the relationship between vascular health and brain aging, potentially addressing underlying mechanisms of age-related cognitive decline.

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