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RESEARCH PAPER / 2025-12-04

Copper-to-zinc ratio predicts incident sarcopenia and adverse health outcomes: Results from I-Lan Longitudinal Aging Study.

Kuan-Yu Peng, Wei-Ju Lee, Chih-Kuang Liang, Li-Ning Peng, Ming-Hsien Lin, Ching-Hui Loh, Fei-Yuan Hsiao, Liang-Kung Chen

Taiwan Semiconductor Manufacturing Company Charity Foundation, Taiwan; Department of Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan; Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan. · pubmed

Abstract

The copper-to‑zinc (Cu/Zn) ratio is linked to inflammation and aging, but longitudinal evidence for sarcopenia remains limited. We examined associations of serum copper (Cu), zinc (Zn), and Cu/Zn ratio with adverse health outcomes and sarcopenia.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that the copper-to-zinc ratio can predict incident sarcopenia and adverse health outcomes. This research is relevant as it explores biomarkers associated with aging and their potential role in predicting age-related conditions, contributing to the understanding of underlying mechanisms of aging.

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