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RESEARCH PAPER / 2025-12-04

Benefit of home-based virtual reality aerobic exercise combined with resistance training for reversing sarcopenia and reducing depression in community-dwelling older adults with sarcopenia: a randomized control trial.

Kornanong Yuenyongchaiwat, Chanakan Chitjamnogchai, Natsinee Sermsinsaithong, Wararat Tavonudomgit, Lucksanaporn Mahawong, Sasipa Buranapuntalug, Preeyaphorn Songsorn, Chusak Thanawattano

Department of Physical Therapy, Faculty of Allied Health Sciences, Thammasat University, Pathum Thani, TH, Thailand; Thammasat University Research Unit, Physical Therapy in Respiratory and Cardiovascular Systems, Thammasat University, Pathum Thani, TH, Thailand. Electronic address: [email protected] of Physical Therapy, Faculty of Allied Health Sciences, Thammasat University, Pathum Thani, TH, Thailand; Thammasat University Research Unit, Physical Therapy in Respiratory and Cardiovascular Systems, Thammasat University, Pathum Thani, TH, Thailand. Electronic address: [email protected]. · pubmed

Abstract

Sarcopenia is a growing concern owing to an aging global population. Older people with depression are at risk for sarcopenia and vice versa. Although physical exercise is key in preventing and managing sarcopenia, virtual reality (VR)-based exercises have emerged as an engaging alternative that may also alleviate depressive symptoms and enhance quality of life in older adults. However, the effects of VR exercise on depression in individuals with sarcopenia who are at higher risk of both physical decline and psychological distress remain underexplored.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that home-based virtual reality aerobic exercise combined with resistance training can reverse sarcopenia and reduce depression in older adults. This research addresses sarcopenia, a significant age-related condition, and explores innovative interventions that could improve health outcomes in the aging population.

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