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RESEARCH PAPER / 2025-12-02

Edentulism as an independent risk factor for sarcopenia: evidence from cross-sectional and longitudinal analyses based on the CHARLS cohort.

Tianyang Zhai, Zhongyi Sun, Qianyang Xie, Yanhui Wu, Huiru Zou, Jing Ni

Tianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction, Tianjin Stomatological Hospital, The Affiliated Stomatological Hospital of Nankai University, Tianjin, China.Tianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction, Tianjin Stomatological Hospital, The Affiliated Stomatological Hospital of Nankai University, Tianjin, China. · pubmed

Abstract

Edentulism and sarcopenia are two highly prevalent, age-related conditions that share common nutritional, inflammatory, and functional pathways. Whether tooth loss independently contributes to the development of sarcopenia-and in which population strata this effect is strongest-remains uncertain, especially in Asian cohorts.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Edentulism is proposed as an independent risk factor for sarcopenia in older adults. This paper is relevant as it explores the relationship between two age-related conditions, potentially contributing to our understanding of factors that influence aging and longevity.

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