Mechanisms and targets of vascular natural aging from a systems biology perspective.
Abstract
Vascular aging is a fundamental biological process underlying many age-related cardiovascular diseases. Although traditional risk factors have been widely studied, vascular dysfunction progresses with aging even in individuals without classic risk factors. Current studies often focus on individual organs or single-cell types and pathways, resulting in limited understanding of the multidimensional mechanisms of vascular aging.
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Research summary
The paper explores the multidimensional mechanisms of vascular aging and identifies potential targets for intervention. This research is relevant as it addresses the underlying biological processes of aging, specifically in the vascular system, which is crucial for understanding and potentially mitigating age-related diseases.
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