Construction of a novel 3-gene diagnostic signature related to senescence in intervertebral disc degeneration.

Haoxi Li, Mingke Wei, Chengqiang Yu, Zhuhai Li, Qie Fan, Shuyu Yao, Yufeng Huang, Jianxun Wei

Department of Spine Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, 530016, China. [email protected] of Spine Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, 530016, China. [email protected]. · pubmed

Paper

Abstract

Numerous studies have manifested that cellular senescence involves in the pathogenesis of intervertebral disc degeneration (IDD). Here, we constructed a novel senescence-related genes (SRGs) signature for IDD.

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Research summary

The paper claims to construct a novel 3-gene diagnostic signature related to senescence in intervertebral disc degeneration. The focus on cellular senescence in the context of intervertebral disc degeneration ties into aging mechanisms, making it relevant to longevity research.

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