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RESEARCH PAPER / 2025-11-26

Lysosomal control of proteostasis and reproductive capacity by conserved LMD-3 protein in

Yile Zhai, Tiantian Wang, Jiangxue Han, Mengxiao Wu, Meixi Gong, Wenfei Li, Zhe Zhang

Institute of Medical Sciences, the Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250033 Shandong, China. · pubmed

Abstract

Human female fertility declines markedly with age, a pattern mirrored in

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that the conserved LMD-3 protein plays a crucial role in regulating lysosomal function, proteostasis, and reproductive capacity, which are essential for understanding the mechanisms of aging. This research addresses fundamental biological processes that could influence longevity and reproductive aging, making it relevant to the field of longevity research.

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