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RESEARCH PAPER / 2025-11-26

Karen McMurdie, Allison N Peeney, Melissa A Mefford, Peter Baumann, David C Zappulla

Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA.Department of Biology, Johns Hopkins University, Baltimore, Maryland, USA. · pubmed

Abstract

The telomerase RNA-protein enzyme is critical for most eukaryotes to complete genome copying by extending chromosome ends, thus solving the end-replication problem and postponing senescence. Despite the importance of the fission yeast

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Research summary

The paper investigates the role of telomerase in extending chromosome ends, which is crucial for addressing the end-replication problem associated with aging. This research is relevant as it explores a fundamental mechanism that could potentially delay senescence and contribute to longevity.

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