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RESEARCH PAPER / 2025-11-26

Impact of skeletal muscle mass index on glycemic progression and remission in Chinese adults with prediabetes: a nationwide cohort study.

Junhui Wan, Xin Huang, Yang Zou, Guotai Sheng, Guobo Xie, Na Zhang

Nephrology Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi Provincial, China. · pubmed

Abstract

Age-related decline in skeletal muscle mass among middle-aged and older adults is a major global public health concern and a critical factor affecting glucose metabolism. This study aims to investigate the association between the skeletal muscle mass index (SMI) and glycemic progression and remission in the middle-aged and older Chinese population with prediabetes.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that higher skeletal muscle mass index is associated with better glycemic outcomes in Chinese adults with prediabetes. This study is relevant as it addresses the role of skeletal muscle mass in glucose metabolism, which is a critical factor in aging and longevity, particularly in the context of age-related metabolic decline.

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