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RESEARCH PAPER / 2025-11-25

Effects of TA-65 on telomere length, functional outcomes, and inflammation: a systematic review and meta-analysis.

Xiaojuan Su, Cheng Wang, Zhixian Gou, Yi Qu

Department of Pediatrics/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education)/NHC Key Laboratory of Chronobiology, West China Second University Hospital, Sichuan University, Chengdu, 610041, China.Department of Pediatrics/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education)/NHC Key Laboratory of Chronobiology, West China Second University Hospital, Sichuan University, Chengdu, 610041, China. · pubmed

Abstract

TA-65®, a telomerase-activating compound derived from Astragalus membranaceus, has garnered interest for its potential to modulate cellular aging. However, its mechanistic efficacy and long-term toxicological profile remain inadequately synthesized.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that TA-65® can positively influence telomere length and related functional outcomes. This research is relevant as it investigates a potential intervention aimed at modulating cellular aging, which aligns with the goals of longevity research.

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