Association of phenotypic age acceleration with risk of sudden cardiac arrest: Evidence from a large retrospective cohort.

Chuxian Guo, Zenghui Zhang, Yan Li, Shaojie Han, Yuanqi Su, Feifei Wang, Jui-Ning Yeh, Panpan Li, Chunyan Jian, Xin Song, Yan Feng, Fangli Wang, Shan Zhuo, Haoran Li, Huimin Zhu, Zhaoyu Liu, Jun Guo

Department of Cardiology, The First Affiliated Hospital, Jinan University, Guangzhou, China. · pubmed

Paper

Abstract

Biological processes of aging significantly contribute to cardiovascular disease (CVD) development. Phenotypic age acceleration (PhenoAgeAccel) is recognized as convenient proxy for biological aging. However, its relationship with sudden cardiac arrest (SCA) remains unclear.

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Research summary

The paper claims that phenotypic age acceleration is associated with an increased risk of sudden cardiac arrest. This research is relevant as it explores the relationship between biological aging and a specific cardiovascular event, potentially linking aging processes to age-related diseases.

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