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RESEARCH PAPER / 2025-11-20

Neural Compensation in Medial Prefrontal Cortex Preserves Self-Prioritization in Aging: A Computational Approach.

Yongfa Zhang, Yang Sun, Haixu Wang, Wanke Pan, Fei Wang, Jie Sui

Department of Psychological and Cognitive Sciences, Tsinghua University, Beijing, 100083, China.Department of Psychological and Cognitive Sciences, Tsinghua University, Beijing, 100083, China. · pubmed

Abstract

Cognitive aging is characterized by widespread decline, yet certain fundamental processes show remarkable resilience. This study demonstrates that older adults (OAs;

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Research summary

The paper claims that neural compensation in the medial prefrontal cortex helps maintain self-prioritization in older adults despite cognitive aging. This research is relevant as it explores mechanisms that could contribute to resilience in cognitive functions during aging, addressing underlying processes rather than merely treating symptoms.

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