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RESEARCH PAPER / 2025-11-17

Autophagic failure with age: influence on metabolic disorders and prospects for therapeutic targeting.

Emma Brand, Mbalenhle Ntuli, Benjamin Loos

Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa.Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa. · pubmed

Abstract

Autophagy, from Greek

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that autophagic failure with age contributes to metabolic disorders and suggests therapeutic targeting as a potential solution. This research addresses a fundamental aspect of aging and its impact on health, focusing on a root cause rather than merely treating symptoms.

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