Phenotypic and metabonomics studies of FMOs in C. elegans and their roles in lifespan extension.

Mohamed Said, Rafael Freire, Filipe Cabreiro, Jose Ivan Serrano-Contreras, Elinor P Thompson, Jeremy R Everett

Faculty of Engineering and Science, University of Greenwich, Chatham Maritime, Kent, ME4 4TB, UK.Faculty of Engineering and Science, University of Greenwich, Chatham Maritime, Kent, ME4 4TB, UK. · pubmed

Paper

Abstract

Flavin-Containing Monooxygenases (FMO) are widely conserved, xenobiotic-detoxifying enzymes whose additional endogenous functions have been revealed in recent studies. Those roles include the regulation of longevity in the model nematode Caenorhabditis elegans.

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Research summary

The paper investigates the role of Flavin-Containing Monooxygenases (FMO) in regulating longevity in C. elegans. This research is relevant as it explores mechanisms that may contribute to lifespan extension, addressing fundamental aspects of aging biology.

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