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RESEARCH PAPER / 2025-11-16

Handgrip Strength Asymmetry Predicts Mortality Risk: A Prospective Cohort Study From the UK Biobank.

Yuling Li, Decheng Li, Ziyang Ren, Chen Chen, Shuai Guo, Zuliyaer Talifu, Xiaoying Zheng

School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.School of Population Medicine and Public Health, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. · pubmed

Abstract

Although low handgrip strength (HGS) is a well-established biomarker of aging and mortality, the prognostic significance of HGS asymmetry remains underexplored. This study sought to determine the associations of HGS asymmetry patterns with frailty, comorbidities, mortality risk, and life expectancy in a large population-based cohort.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Handgrip strength asymmetry is associated with increased mortality risk and frailty. The study explores a biomarker of aging that could provide insights into longevity and mortality risk, making it relevant to the field of aging research.

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