Probiotics Ameliorate Aging-Related Cognitive Impairments and Pathological Changes through Alleviating Telomere Attrition and Enhancing Mitochondrial Function in Senescence-Accelerated Mouse Prone 8 Mice.

Siquan Zhou, Shufang Shan, Ruirui Li, Xiaoyu Wang, Jingyuan Xiong, Guo Cheng

West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China. · pubmed

Abstract

Aging-related cognitive impairment, characterized by DNA damage and mitochondrial dysfunction, still lacks effective treatment strategies. Recent findings suggest that

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Research summary

Probiotics can improve cognitive function and reduce aging-related pathological changes by mitigating telomere attrition and enhancing mitochondrial function. The study addresses mechanisms that could potentially reverse aspects of aging rather than merely treating symptoms of age-related diseases.

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