Association of muscle mass and strength with blood-based epigenetic aging among middle-aged and older adults in the United States.
Abstract
Muscle mass and strength influence various age-related health outcomes, however their individual and joint associations with biological aging remain understudied. This study investigated the associations of muscle health with epigenetic aging based on DNA methylation in blood samples, among middle-aged and older adults. We analyzed data from 1,121 individuals from the 1999-2002 cycles of the National Health and Nutrition Examination Survey. Muscle mass was assessed using the appendicular skeletal muscle mass index, with low muscle mass defined as < 7.0 kg/m
The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.
Research summary
The paper claims that muscle mass and strength are associated with biological aging as measured by DNA methylation in blood samples. This research is relevant as it explores the relationship between muscle health and biological aging, which could provide insights into the underlying mechanisms of aging and potential interventions for age-related health outcomes.
Author of this paper? Send a correction.