Interaction between genetic predisposition to successful ageing and chronic air pollution on lung disease in elderly women: results of the German SALIA cohort.

Sara Kress, Michael Lau, Claudia Wigmann, Michael J Abramson, Holger Schwender, Tamara Schikowski

IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.IUF - Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany. · pubmed

Paper

Abstract

To investigate the interplay between the genetic predisposition to successful ageing and air pollution on lung disease in healthy aged German women under the hypothesis that ageing and lung diseases share mechanisms of oxidative stress and inflammation that can be regulated by genetic predisposition and environmental factors.

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Research summary

The paper investigates the interaction between genetic predisposition to successful aging and chronic air pollution on lung disease in elderly women. This research is relevant as it explores the interplay of genetic and environmental factors in aging-related diseases, addressing potential root causes of aging mechanisms.

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