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RESEARCH PAPER / 2025-11-01

Oral-Sarcopenia nexus in health disparities: chewing and blood mediated pathways in a Chinese aging cohort.

Yong Xiang, Guosong Wang, Yiting Cheng, Yuhan Zhang, Jialiang Zhao, Birong Dong, He Cai, Li Cheng, Tao Hu

State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, West China Hospital of Stomatology, Sichuan University, Chengdu, China.State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Frontier Innovation Center for Dental Medicine Plus, West China Hospital of Stomatology, Sichuan University, Chengdu, China. · pubmed

Abstract

Aging affects oral health and skeletal muscle, but the associations between oral diseases and possible sarcopenia remain understudied, especially in low-income regions. Thus, the study aimed to explore this relationship and potential mediating pathways.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the relationship between oral health and sarcopenia in an aging cohort, suggesting that oral diseases may contribute to muscle deterioration. This research addresses a potential root cause of aging-related health disparities, which is crucial for understanding and improving longevity outcomes.

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