Tardigrade Dsup extends

Myriam Richaud, Rohit Shrivastava, Dimitris Xirodimas, Simon Galas, Aymeric Bailly

IBMM, University of Montpellier, CNRS, ENSCM, Montpellier, France. · pubmed

Abstract

Tardigrades survive extreme environments partly through the damage suppressor (Dsup) protein, which protects DNA from ionizing radiation and oxidative stress. Dsup is largely unstructured but binds nucleosomes to shield DNA from damage. To investigate its protective role in a whole organism, we expressed the

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Research summary

The paper claims that the Dsup protein from tardigrades protects DNA from damage in a whole organism. This research is relevant as it explores a mechanism that could potentially mitigate age-related DNA damage, which is a significant factor in the aging process.

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