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RESEARCH PAPER / 2025-10-30

Exploring a crossroads in the aging process.

Kiyan Shabestary, Daniel E Gottschling

Calico Life Sciences LLC, San Francisco, United States.Calico Life Sciences LLC, San Francisco, United States. · pubmed

Abstract

Experiments on yeast show that the nuclear pore complex has a central role in the loss of chromosomes associated with aging.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that the nuclear pore complex plays a central role in the loss of chromosomes associated with aging. This research addresses a potential root cause of aging by exploring cellular mechanisms, which is relevant to longevity research.

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