Multi-omic profiling reveals age-related immune dynamics in healthy adults.

Qiuyu Gong, Mehul Sharma, Marla C Glass, Emma L Kuan, Aishwarya Chander, Mansi Singh, Lucas T Graybuck, Zachary J Thomson, Christian M LaFrance, Samir Rachid Zaim, Tao Peng, Lauren Y Okada, Palak C Genge, Katherine E Henderson, Elisabeth M Dornisch, Erik D Layton, Peter J Wittig, Alexander T Heubeck, Nelson M Mukuka, Julian Reading, Garrett Strawn, Teminijesu Titus-Adewunmi, Kathleen Abadie, Charles R Roll, Veronica Hernandez, Vaishnavi Parthasarathy, Tyanna J Stuckey, Blessing Musgrove, Elliott Swanson, Cara Lord, Morgan D A Weiss, Cole G Phalen, Regina R Mettey, Kevin J Lee, John B Johanneson, Erin K Kawelo, Jessica Garber, Upaasana Krishnan, Megan Smithmyer, E John Wherry, Laura A Vella, Sarah E Henrickson, Mackenzie S Kopp, Adam K Savage, Lynne A Becker, Paul Meijer, Ernest M Coffey, Jorg J Goronzy, Mikael Sigvardsson, Cate Speake, Thomas F Bumol, Ananda W Goldrath, Troy R Torgerson, Xiao-Jun Li, Peter J Skene, Jane H Buckner, Claire E Gustafson

Allen Institute for Immunology, Seattle, WA, USA.Allen Institute for Immunology, Seattle, WA, USA. · pubmed

Paper

Abstract

The generation and maintenance of immunity is a dynamic process that is dependent on age

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims to reveal age-related immune dynamics in healthy adults through multi-omic profiling. This research is relevant as it explores the underlying immune changes associated with aging, which could contribute to understanding the biological mechanisms of aging and potential interventions.

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