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RESEARCH PAPER / 2025-10-25

Age-related changes in mitochondrial markers and telomere dynamics during initial growth of human preantral follicles.

Luciana Cacciottola, Manyu Zhang, Lara Houeis, Caroline Bouzin, Marie-Astrid van Dievoet, Mathieu Luyckx, Jacques Donnez, Marie-Madeleine Dolmans

Gynecology Research Unit, Institut de Recherche Expérimentale Et Clinique, Université Catholique de Louvain, Avenue Mounier 52, Bte. B1.52.02, Brussels, 1200, Belgium.Gynecology Research Unit, Institut de Recherche Expérimentale Et Clinique, Université Catholique de Louvain, Avenue Mounier 52, Bte. B1.52.02, Brussels, 1200, Belgium. · pubmed

Abstract

To investigate how mitochondria and telomeres evolve during early follicle growth in human preantral follicles, and how these changes relate to reproductive age.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the evolution of mitochondrial markers and telomere dynamics during early follicle growth in human preantral follicles. This research is relevant as it explores cellular mechanisms associated with aging and reproductive health, which can contribute to understanding the biological processes underlying longevity.

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